Safety and Environmental Technology Group

von Goetz, Natalie, Dr.

ETH Zürich
Dr. Natalie von Goetz
Inst. f. Chemie- u. Bioing.wiss.
HCI G 129
Vladimir-Prelog-Weg 1
8093 Zuerich

Phone: +41 44 632 09 75


Human exposure analysis

* new methodology for assessing aggregate consumer exposure

* exposure modelling for emerging chemicals with toxicological effects at low concentrations (e.g. endocrine disrupting chemicals)

Advisory boards

External expert in SCCS Working group "Cosmetic Ingredients" (since 2015)

External expert in SCCS Working group "Nanomaterials in cosmetics" (since 2014)

Expert panel Kommission Expo of the German Bundesamt für Risikobewertung (BfR) (since 2014)

External expert in EFSA-Working group on “Uncertainty in Risk Assessment“ (since 2013)

Exernal expert in EFSA-Working group on Bisphenol A (2012-2015)


"Consumer exposure assessment" in ETH-Course "Substance-oriented risk analysis" with Prof. K Hungerbühler (ETHZ) (since 2012)

"Risk analysis of chemicals" in ETH-Course "Ecological systems ananlysis" with Prof. S Hellweg (ETHZ) (since 2016)

“Consumer exposure modeling” in advanced studies programme “Regulatory Science” of the Swiss Centre of Toxicology (SCAHT), 2015

“Environmental exposure modeling” in advanced studies programme “Regulatory Science” of the Swiss Centre of Toxicology (SCAHT), 2015

"Risk analysis of chemicals" in ETH-Course "Analysis and Evaluation of Environmental Sustainability" (2011-2014)

Curriculum Vitae

ETH Zürich: Consumer Exposure Assessment, Group Leader "Human Exposure Analysis" (since 2008)

BASF AG, Ludwigshafen: Expert for Environmental Exposure Modeling, Laboratory Manager, Expert for the Fate of Plant Protection Products in the Environment (1997-2007)

TU Braunschweig: PhD- Thesis "Regionalisation of pesticide decay in soil" (1997)

Uni Heidelberg: Diploma in Chemistry, Diploma thesis "Molecular Modelling of Cobalt-tripod-complexes" (1992)



Dudzina T, Delmaar C, Biesterbos J, Bakker M, Bokkers B, Scheepers P, van Engelen J, Hungerbuehler K, von Goetz N (2015)The probabilistic aggregate consumer exposure model (PACEM): Validation and comparison to a lower-tier assessment for the cyclic siloxane D5, Environment International, 79,8-16.

Manova E, von Goetz N, Hungerbuehler K (2015) Aggregate consumer exposure to UV filter ethylhexyl methoxycinnamate via personal care products, Environment International, 74, 249–257.

Biesterbos J, Beckmann G, van Wel L, Anzion R, von Goetz N, Dudzina T, Roeleveld N, Ragas A, Russel F, Scheepers P (2015):Aggregate dermal exposure to cyclic siloxanes in personal care products: Implications for risk assessment, Environment International, 74, 231-239.

Bachler G, von Goetz N, Hungerbuehler K (2015) Using physiologically based pharmacokinetic (PBPK) modeling for dietary risk assessment of titanium dioxide (TiO2) nanoparticles , Nanotoxicology, 9 (3), 373-380.

Manova E, von Goetz N, Hungerbuehler K (2014) Ultraviolet filter contact and photocontact allergy: consumer exposure and risk assessment for octocrylene from personal care products and sunscreens, Br J Dermatol., 171, 1368–1374.

Lombi E, Donner E, Scheckel K, Sekine R, Lorenz C, von Goetz N, Nowack B (2014) Silver speciation and release in commercial antimicrobial textiles as influenced by washing, Chemosphere, 111, 352–358.

Losert S, von Goetz N, Bekker C, Fransmann W, Wijnhoven S, Delmaar C, Hungerbuehler K, Ulrich A (2014) Human exposure to conventional and nanoparticle-containing sprays - a critical review, Environmental Science & Technology, 48, 5366–5378.

Dudzina T, von Goetz N, Bogdal C, Biesterbos J, Hungerbühler K (2014) Concentrations of cyclic volatile methylsiloxanes in European cosmetics and personal care products: Prerequisite for human and environmental exposure assessment, Environment International, 62, 86-94.

Bachler G, von Goetz N, Hungerbühler K (2013) A physiologically based pharmacokinetic model for ionic silver and silver nanoparticles, International Journal of Nanomedicine, 8, 3365–3382.

Manová E, von Goetz N, Keller C, Siegrist M, Hungerbühler K (2013) Use patterns of leave-on personal care products among Swiss-German children, adolescents, and adults, International Journal of Environmental Research and Public Health, 10, 2778–2798.

von Goetz N, Fabricius L, Glaus R, Weitbrecht V, Günther D, Hungerbühler K (2013) Migration of silver from commercial plastic food containers and implications for consumer exposure assessment, Food Additives & Contaminants: Part A, 30, 612–620.

von Goetz N, Lorenz C, Windler L, Nowack B, Heuberger MP, Hungerbühler K (2013) Migration of Ag- and TiO2-(nano)particles from textiles into artificial sweat under physical stress: Experiments and exposure modeling, Environ. Sci. Technol., 2013, 47 (17), pp 9979–9987.

Biesterbos J, Dudzina T, Delmaar C, Bakker M, Russel F, von Goetz N, Scheepers P, Roeleveld N (2013) Usage patterns of personal care products: important factors for exposure assessment, Food and Chemical Toxicology, 55, 8-17.

Manova E, von Goetz N, Hauri U, Bogdal C, Hungerbühler K (2013) Organic UV filters in personal care products in Switzerland: A survey of occurrence and concentrations. International Journal of Hygiene and Environmental Health, 216, 508-514.

Windler L, Lorenz C, von Goetz N, Hungerbühler K, Amberg M, Heuberger M, Nowack B (2012) Release of titanium dioxide from textiles during washing, Environmental Science & Technology, 46 (15), 8181-8188.

Lorenz C, Windler L, von Goetz N, Lehmann RP, Schuppler M, Hungerbühler K, Heuberger M, Nowack B (2012) Characterization of silver release from commercially available functional (nano)textiles Chemosphere, 89 (7), 817-824.

Weir A, Westerhoff P, Fabricius L, Hristovski K, von Goetz N (2012) Titanium dioxide nanoparticles in food and personal care products, Environmental Science & Technology, 46 (4), 2242-2250.

Lorenz C, Hagendorfer H, von Goetz N, Kaegi R, Gehrig R, Ulrich A, Scheringer M, Hungerbühler K (2011) Nanosized aerosols from consumer sprays: experimental analysis and exposure modeling for four commercial products Journal for Nanoparticle Research, 13, 3377-3391.

Trudel D, Tlustos C, von Goetz N, Scheringer M, Reichert P, Hungerbühler K (2011) Exposure of the Irish population to PBDEs in food: consideration of parameter uncertainty and variability for risk assessment, Food Additives & Contaminants: Part A 28, 943–955.

Trudel D, Scheringer M, von Goetz N, Hungerbühler K (2011) Total consumer exposure to polybrominated diphenyl ethers in North America and Europe,
Environmental Science & Technology 45, 2391–2397.

Trudel D, Tlustos C, von Goetz N, Scheringer M, Hungerbühler K (2011) PBDE exposure from food in Ireland: Optimizing data exploitation in probabilistic exposure modelling, Journal of Exposure Science and Environmental Epidemiology, 21, 565-575.

Hagendorfer H, Lorenz C, Kaegi R, Sinnet B, Gehrig R, von Goetz N et al. (2010) Size fractionated characterization and quantification of nanoparticle release rates from a consumer spray product containing engineered nanoparticles, Journal for Nanoparticle Research, 12 (7), 2481-2494.

Lorenz C, von Goetz N, Scheringer M, Wormuth M, & Hungerbühler K (2011) Potential exposure of German consumers to engineered nanoparticles in cosmetics and personal care products, Nanotoxicology, 5 (1), 12-29.

Lorenz C, Tiede K, Tear S, Boxall A, von Goetz N, & Hungerbühler K. (2010) Imaging and Characterization of Engineered Nanoparticles in Sunscreens by Electron Microscopy, Under Wet and Dry Conditions, International Journal of Occupational and Environmental Health, 16 (4), 406-428.

Schmidt B, Th Neuffer, M Häfner, F Dechet, Th Küchler, B Peters, H Resseler, N von Götz (2005) Evaluation of plant protection product findings in groundwater in Germany, Nachrichtenbl. Deut. Pflanzenschutzd., 57 (11), S. 213–223.

von Goetz N, M Wormuth, M Scheringer & K Hungerbühler (2010) Bisphenol A: How the most relevant exposure sources contribute to total consumer exposure, Risk Analysis, 30, No. 3, 473-487

Von Götz N, P Nörtersheuser & O Richter (1999) Population based analysis of pesticide kinetics, Chemosphere, 38, No. 7, 1615-1630.

Von Götz N & O Richter (1999) Simulation of herbicide degradation in different soils by use of pedo-transfer functions (PTF) and non-linear kinetics, Chemosphere, 38, No. 6, 1401-1407.


Von Götz, N. (1997): Regionalisierung des Herbizidabbaus im Boden unter besonderer Berücksichtigung von Bentazon –Datenerhebung und Modellbildung-. Schriftenreihe Landschaftsökologie und Umweltforschung, Heft 28, Selbstverlag Institut für Geographie und Geoökologie der TU Braunschweig.

Conference papers (selected)

Von Götz, N., M. Wormuth, M. Scheringer, K. Hungerbühler (2008): Consumer Exposure to Bisphenol A: Total Exposure Levels relating to Everyday Life of the General Western European Population, SETAC-GLB, Frankfurt/M, Germany.

Von Götz, N. (2005): Entwicklung von Pflanzenschutzmitteln: Vorgehen und Problematik, Proceedings of LUBW-Conference "Pflanzenschutzmittel und Gewässer", Bayerische Landesanstalt für Wasserforschung, München (Hrsg.)

Richter, O. & N. von Götz (1996): Prediction of herbicide kinetics by means of a Fuzzy Expert system. Proceedings of the X Symposium on Pesticide Chemistry, Piacenza, Italia, 425-432.

Von Götz, N., O. Richter (1996): Vorhersage von Herbizidkinetiken durch ein FUZZY-Expertensystem, Z. PflKrankh. PflSchutz, Sonderh. XV, 635-641.


Höck J, Epprecht T, Hofmann H, Höhner K, Krug HF, Lorenz C, Limbach L, Gehr P, Nowack B, Riedicker M, Schirmer K, Schmid B, Som C, Stark W, Studer C, Ulrich A, von Götz N, Wengert S, Wick P (2010). Guidelines on the Precautionary Matrix for Synthetic Nanomaterials, Version 2.


Wichtiger Hinweis:
Diese Website wird in älteren Versionen von Netscape ohne graphische Elemente dargestellt. Die Funktionalität der Website ist aber trotzdem gewährleistet. Wenn Sie diese Website regelmässig benutzen, empfehlen wir Ihnen, auf Ihrem Computer einen aktuellen Browser zu installieren. Weitere Informationen finden Sie auf
folgender Seite.

Important Note:
The content in this site is accessible to any browser or Internet device, however, some graphics will display correctly only in the newer versions of Netscape. To get the most out of our site we suggest you upgrade to a newer browser.
More information

© 2016 ETH Zurich | Imprint | 17 March 2016